Cigarette Smoking and ARDS After Blunt Trauma: The Influence of Changing Smoking Patterns and Resuscitation Practices.

ABSTRACT:

Background

Cigarette smoking is associated with an increased risk of developing ARDS. However, whether changes in smoking patterns or processes of care impact this relationship is unclear.

Research question

Are changes in smoking and resuscitation patterns associated with changes in the relationship between smoking and ARDS?

Study design and methods

We conducted a prospective cohort study of critically injured adults with blunt trauma from 2005 to 2015. Plasma cotinine, a tobacco biomarker, was measured to categorize patients by smoking status. We used regression to assess the relationship between smoking, resuscitation practices, and ARDS over time.

Results

In the overall cohort, active (OR, 1.9; 95% CI, 1.0-3.5; P = .046) and passive (OR, 2.6; 95% CI, 1.4-4.8

SUBMITTER: Moazed F 

PROVIDER: S-EPMC7545485 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature