Rationally designed dual-plasmonic gold nanorod@cuprous selenide hybrid heterostructures by regioselective overgrowth for in vivo photothermal tumor ablation in the second near-infrared biowindow.

ABSTRACT: NIR-II plasmonic materials offer multiple functionalities for in vivo biomedical applications, such as photothermal tumor ablation, surface-enhanced Raman scattering biosensing, photoacoustic imaging, and drug carriers. However, integration of noble metals and plasmonic semiconductors is greatly challenging because of the large lattice-mismatch. This study reports the regioselective overgrowth of Cu_2-xSe on gold nanorods (GNRs) for preparation of dual-plasmonic GNR@Cu_2-xSe hybrid heterostructures with tunable NIR-II plasmon resonance absorption for in vivo photothermal tumor ablation. Methods: The regioselective deposition of amorphous Se and its subsequent conversion into Cu_2-xSe on the GNRs are performed by altering capping agents to

SUBMITTER: Shan B 

PROVIDER: S-EPMC7546011 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature