In Vivo Visualization of Eye Vasculature Using Super-Resolution Ultrasound Microvessel Imaging.

ABSTRACT:

Objective

The choroidal vessels, which supply oxygen and nutrient to the retina, may play a pivotal role in eye disease pathogenesis such as diabetic retinopathy and glaucoma. In addition, the retrobulbar circulation that feeds the choroid shows an important pathophysiologic role in myopia and degenerative myopia. Owing to the light-absorbing retinal pigment epithelium (RPE) and optically opaque sclera, choroidal and retrobulbar vasculature were difficult to be observed using clinically accepted optical coherence tomography angiography (OCT-A) technique. Here, we have developed super-resolution ultrasound microvessel imaging technique to visualize the deep ocular vasculature.

Methods

An 18-MHz linear array transducer with compounding plane wave imaging technique and contrast

SUBMITTER: Qian X 

PROVIDER: S-EPMC7546097 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature