Parental, Perinatal, and Childhood Risk Factors for Development of Irritable Bowel Syndrome: A Systematic Review.

ABSTRACT:

Background/aims

Adverse early life experiences are associated with the development of stroke, cancer, diabetes, and chronic respiratory and ischemic heart diseases. These negative experiences may also play a role in the development of irritable bowel syndrome (IBS)--a functional gastrointestinal disease. This review discusses the research to date on the parental, perinatal, and childhood risk and protective factors associated with the development of IBS.

Methods

A literature search was completed for studies published between 1966 and 2018 that investigated premorbid factors occurring during the perinatal and childhood periods as well as parental factors that were associated with the development of IBS.

Results

Twenty-seven studies fulfilled the review criteria. Risk f

SUBMITTER: Low EXS 

PROVIDER: S-EPMC7547188 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature