Integrated analysis of serum lipid profile for predicting clinical outcomes of patients with malignant biliary tumor.

ABSTRACT:

Background

Serum lipids were reported to be the prognostic factors of various cancers, but their prognostic value in malignant biliary tumor (MBT) patients remains unclear. Thus we aim to assess and compare prognosis values of different serum lipids, and construct a novel prognostic nomogram based on serum lipids.

Methods

Patients with a confirmed diagnosis of MBT at our institute from 2003 to 2017 were retrospectively reviewed. Prognosis-related factors were identified via univariate and multivariate Cox regression analyses. Then the novel prognostic nomogram and a 3-tier staging system were constructed based on these factors and further compared to the TNM staging system.

Results

A total of 368 patients were included in this study. Seven optimal survival-related fac

SUBMITTER: Sun L 

PROVIDER: S-EPMC7547451 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature