A high salt meal does not impair cerebrovascular reactivity in healthy young adults.

ABSTRACT: A high sodium (Na⁺ ) meal impairs peripheral vascular function. In rodents, chronic high dietary Na⁺ impairs cerebral vascular function, and in humans, habitual high dietary Na⁺ is associated with increased stroke risk. However, the effects of acute high dietary Na⁺ on the cerebral vasculature in humans are unknown. The purpose of this study was to determine if acute high dietary Na⁺ impairs cerebrovascular reactivity in healthy adults. Thirty-seven participants (20F/17M; 25 ± 5 years; blood pressure [BP]: 107 ± 9/61 ± 6 mm Hg) participated in this randomized, cross-over study. Participants were given a low Na⁺ meal (LSM; 138 mg Na⁺ ) and a high Na⁺ meal (HSM; 1,495 mg Na⁺ ) separated by ≥ on

SUBMITTER: Migdal KU 

PROVIDER: S-EPMC7547584 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature