Fluid management in ARDS: an evaluation of current practice and the association between early diuretic use and hospital mortality.

ABSTRACT:

Background

Acute respiratory distress syndrome (ARDS) and volume overload are associated with increased hospital mortality. Evidence supports conservative fluid management in ARDS, but whether current practice reflects the implementation of that evidence has not been described. This study reports the variability in contemporary fluid management for ICU patients with ARDS. We compared routine care to trial protocols and analyzed whether more conservative management with diuretic medications in contemporary, usual care is associated with outcomes.

Methods

We performed a retrospective cohort study in nine ICUs at two academic hospitals during 2016 and 2017. We included 234 adult patients with ARDS in an ICU at least 3 days after meeting moderate-severe ARDS criteria (PaO_2<

SUBMITTER: Seitz KP 

PROVIDER: S-EPMC7549083 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature