Graft Function, Albuminuria, and the Risk of Hemorrhage and Thrombosis After Kidney Transplantation.

ABSTRACT:

Background

Compared to the general population, kidney transplant recipients are at increased risk of hemorrhage and thrombosis. Whether this risk is affected by graft function and albuminuria is unknown.

Objective

To determine the association between graft function and albuminuria and the risk of post-transplant hemorrhage and thrombosis.

Design

Retrospective cohort study.

Setting

We used linked health care databases in Alberta, Canada.

Patients/sample/participants

We included adult kidney transplant recipients from 2002 to 2015 with a functioning graft at 1 year.

Measurements

Estimated glomerular filtration rate (eGFR) and albuminuria measurements at 1 year post-transplant were used to categorize recipients (eGFR: ≥45 vs. <45 mL/min/1.73 m^2<

SUBMITTER: Jeong R 

PROVIDER: S-EPMC7549159 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature