Diagnostic Role of Mean-Platelet Volume in Acute Pulmonary Embolism: A Meta-analysis and Systematic Review.

ABSTRACT:

Background

Acute pulmonary embolism (PE) is the third most fatal cardiovascular disease. PE is frequently misdiagnosed due to its clinical presentation's heterogeneity and the inexistence of biomarkers for its immediate diagnosis. Mean platelet volume (MPV) has shown a potential role as a biomarker in acute PE. In this analysis, we aimed to systematically compare the MPV in patients with and without definite diagnosis of PE, in emergency departments.

Methods

Embase, PubMed and Medline were searched for relevant publications, in English. The main inclusion criteria were studies which compared MPV in patients with acute PEA versus a control group.

Results

Thirteen studies consisting of a total number of 2428 participants were included. Of the participants included, 1316

SUBMITTER: Febra C 

PROVIDER: S-EPMC7549176 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature