Early hyperoxemia is associated with lower adjusted mortality after severe trauma: results from a French registry.

ABSTRACT:

Background

Hyperoxemia has been associated with increased mortality in critically ill patients, but little is known about its effect in trauma patients. The objective of this study was to assess the association between early hyperoxemia and in-hospital mortality after severe trauma. We hypothesized that a PaO₂ ≥ 150 mmHg on admission was associated with increased in-hospital mortality.

Methods

Using data issued from a multicenter prospective trauma registry in France, we included trauma patients managed by the emergency medical services between May 2016 and March 2019 and admitted to a level I trauma center. Early hyperoxemia was defined as an arterial oxygen tension (PaO₂) above 150 mmHg measured on hospital admission. In-hospital mortality was compare

SUBMITTER: Baekgaard JS 

PROVIDER: S-EPMC7549241 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature