Toward a more reliable characterization of fractal properties of the cerebral cortex of healthy subjects during the lifespan.

ABSTRACT: The cerebral cortex manifests an inherent structural complexity of folding. The fractal geometry describes the complexity of structures which show self-similarity in a proper interval of spatial scales. In this study, we aimed at evaluating in-vivo the effect of different criteria for selecting the interval of spatial scales in the estimation of the fractal dimension (FD) of the cerebral cortex in T₁-weighted magnetic resonance imaging (MRI). We compared four different strategies, including two a priori selections of the interval of spatial scales, an automated selection of the spatial scales within which the cerebral cortex manifests the highest statistical self-similarity, and an improved approach, based on the search of the interval of spatial scales which presents the highes

SUBMITTER: Marzi C 

PROVIDER: S-EPMC7550568 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature