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Improving Successful Introduction after a Negative Food Challenge Test: How to Achieve the Best Result?


ABSTRACT: Oral food challenges (OFC) confirm or exclude the presence of a food allergy. The outcome can be positive (allergic symptoms), inconclusive, or negative (no symptoms). In the case of a negative OFC, parents and children are advised to introduce the challenged food allergen into their diet. However, previous studies showed difficulties in a successful introduction at home. The aim of this prospective non-randomized intervention study is to evaluate the effect of a new strategy with more guidance regarding the dietary introduction after a negative food challenge test. We compared two cohorts: an historical (retrospective) control group of 157 children, previously described, who did not receive any special advice after a negative OFC, versus a new cohort consisting of 104 children, who were g

SUBMITTER: Emons J 

PROVIDER: S-EPMC7551318 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature