A Rapid and International Applicable Diagnostic Device for Cobra (Genus Naja) Snakebites.

ABSTRACT: Cobra snakes (genus Naja) are some of the most dangerous snake species in Asia and Africa, as their bites cause severe life-threatening respiratory failure and local tissue destruction, especially in the case of late diagnosis. The differential diagnosis of snakebite envenomation still mainly relies upon symptomatology, the patient's description, and the experience of physicians. We have designed a rapid test, immunochromatographic test of cobra (ICT-Cobra), which obtained fair results in improving the diagnosis and treatment of Naja (N.) atra snakebites in Taiwan. In this study, we further investigated the feasibility of applying the kit for the detection of other cobra venoms based on the potential interspecies similarity. We firstly demonstrated the cross-reactivity between eight venoms

SUBMITTER: Lin JH 

PROVIDER: S-EPMC7551368 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature