Achilles' Heel of SARS-CoV-2 Structure.
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ABSTRACT:
SUBMITTER: Fernandez A
PROVIDER: S-EPMC7552172 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Publications
Achilles' Heel of SARS-CoV-2 Structure.
ACS pharmacology & translational science 20200915 5
Guided by evolutionarily signaled vulnerabilities in the structure of SARS-CoV-2, we identify epitopes in free monomers of the spike protein that steer the generation of induced or administered antibodies geared at promoting destabilization of the virus quaternary structure, thereby hampering infectivity. ...[more]
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