Blood pressure and mortality in patients with type 2 diabetes and a recent coronary event in the ELIXA trial.

ABSTRACT:

Background

The relationship between blood pressure and mortality in type 2 diabetes (T2DM) is controversial, with concern for increased risk associated with excessively lowered blood pressure.

Methods

We evaluated whether prior cardiovascular disease (CVD) altered the relationship between baseline blood pressure and all-cause mortality in 5852 patients with T2DM and a recent acute coronary syndrome (ACS) who participated in the ELIXA (Evaluation of Lixisenatide in Acute Coronary Syndrome) trial. Risk of death was assessed in Cox models adjusted for age, sex, race, heart rate, BMI, smoking, diabetes duration, insulin use, HbA1c, eGFR, brain natriuretic peptide (BNP), urine albumin/creatinine ratio, treatment allocation and prior coronary revascularization.

Results

Alth

SUBMITTER: Wijkman MO 

PROVIDER: S-EPMC7552471 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature