Tocilizumab for treating COVID-19: a systemic review and meta-analysis of retrospective studies.

ABSTRACT:

Objectives

COVID-19 has become a global epidemic, and effective therapies have not been discovered up to now. We conducted this study to explore the effectiveness and safety of tocilizumab recently used for treating COVID-19.

Method

A comprehensive search was conducted (up to September 27, 2020), and 19 eligible records were identified according to the inclusion and exclusion criteria. The data of the studies were extracted by 2 independent reviewers and were analyzed to evaluate the safety and availability of tocilizumab for treating COVID-19.

Results

Thirteen retrospective case-control studies (n = 2285 patients) and 6 retrospective single-armed studies (n = 208) were retrieved in this study. In the comparison of tocilizumab treatment group (TCZ) and standard treatm

SUBMITTER: Zhao M 

PROVIDER: S-EPMC7553373 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature