Myocardial Dysfunction Is Independently Associated With Mortality in Pediatric Septic Shock.

ABSTRACT:

Objectives

Circulatory dysfunction has been associated with mortality in children with septic shock. However, the mortality risk attributable to myocardial dysfunction per se has not been established, and the association between myocardial dysfunction and mortality is confounded by illness severity. The objective was to determine if sepsis-associated myocardial dysfunction defined by low left ventricular ejection fraction or global longitudinal strain is associated with mortality in pediatric septic shock after adjusting for baseline mortality probability.

Design

Retrospective, observational study.

Setting

Single-center, quaternary-care PICU.

Patients

Children less than 18 years old admitted to the PICU from 2003 to 2018 who had an echocardiogram performed with

SUBMITTER: Lautz AJ 

PROVIDER: S-EPMC7553396 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature