Early and late effects of electroconvulsive therapy associated with different temporal lobe structures.

ABSTRACT: Recent studies examining electroconvulsive therapy (ECT) have reported that early sessions can induce rapid antidepressant and antipsychotic effects, and the early termination of ECT was reported to increase the risk of relapse. We hypothesized that different neural mechanisms associated with the therapeutic effects of ECT may be involved in the different responses observed during the early and late periods of ECT treatment. We investigated whether these antidepressant and antipsychotic effects were associated with temporally and spatially different regional gray matter volume (GMV) changes during ECT. Fourteen patients with major depressive disorder, with or without psychotic features, underwent 3-Tesla structural magnetic resonance imaging scans before (time point [Tp] 1), after the fift

SUBMITTER: Yamasaki S 

PROVIDER: S-EPMC7553938 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature