Cardioprotective properties of leptin in patients with excessive body mass.

ABSTRACT:

Background

Adipose tissue is producing adipokines that play different roles in the pathophysiology of cardiovascular disease.

Aims

The study aimed to assess the role of selected biomarkers in hypertensive patients with overweight and obesity compared with those with normal body-mass index (BMI).

Methods

A total of 62 patients with BMI < 25 kg/m² (median age 54 (46-58) yrs., 57% males) and 51 with BMI ≥ 25 kg/m² (median age 53 (48-59) yrs., 37% males) were enrolled. Biochemical parameters, leptin, adiponectin, and resistin; asymmetric dimethylarginine; interleukin 6; and N-terminal propeptide of type III procollagen, were assessed in plasma. The evaluation of hemodynamic parameters was performed using SphygmoCor 9.0 tonometer. Echocardiography was

SUBMITTER: Paduszynska A 

PROVIDER: S-EPMC7554003 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature