Esophagogastric Junction Opening Parameters Are Consistently Abnormal in Untreated Achalasia.

ABSTRACT: Achalasia is a disorder of impaired lower esophageal sphincter (LES) relaxation and failed peristalsis traditionally characterized by manometry.¹ As impaired LES relaxation is a mechanism of reduced esophagogastric junction (EGJ) opening, abnormally reduced EGJ distensibility assessed with functional luminal imaging probe (FLIP) was reported among patients with untreated achalasia.^2-5 Therefore, we aimed to describe the performance characteristics of EGJ opening parameters on FLIP panometry among a large cohort of treatment-naïve achalasia patients.

SUBMITTER: Rooney KP 

PROVIDER: S-EPMC7554071 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature