Dietary inflammatory potential in relation to the gut microbiome: results from a cross-sectional study.

ABSTRACT: Diet has direct and indirect effects on health through inflammation and the gut microbiome. We investigated total dietary inflammatory potential via the literature-derived index (Dietary Inflammatory Index (DII®)) with gut microbiota diversity, composition and function. In cancer-free patient volunteers initially approached at colonoscopy and healthy volunteers recruited from the medical centre community, we assessed 16S ribosomal DNA in all subjects who provided dietary assessments and stool samples (n 101) and the gut metagenome in a subset of patients with residual fasting blood samples (n 34). Associations of energy-adjusted DII scores with microbial diversity and composition were examined using linear regression, permutational multivariate ANOVA and linear discriminant analysis. Spear

SUBMITTER: Zheng J 

PROVIDER: S-EPMC7554089 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature