UHPLC-MS/MS-Based Nontargeted Metabolomics Analysis Reveals Biomarkers Related to the Freshness of Chilled Chicken.

ABSTRACT: To identify metabolic biomarkers related to the freshness of chilled chicken, ultra-high-performance liquid chromatography-mass spectrometry (UHPLC-MS/MS) was used to obtain profiles of the metabolites present in chilled chicken stored for different lengths of time. Random forest regression analysis and stepwise multiple linear regression were used to identify key metabolic biomarkers related to the freshness of chilled chicken. A total of 265 differential metabolites were identified during storage of chilled chicken. Of these various metabolites, 37 were selected as potential biomarkers by random forest regression analysis. Receiver operating characteristic (ROC) curve analysis indicated that the biomarkers identified using random forest regression analysis showed a strong correlation wit

SUBMITTER: Zhang T 

PROVIDER: S-EPMC7555583 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature