Identification of Hsa_circ_0104824 as a Potential Biomarkers for Breast Cancer.

ABSTRACT:

Background

To study the specific expression of circular RNA (circRNA) in breast cancer and adjacent normal tissues to identify differentially expressed circRNA in breast cancer patients. To study the correlation between circRNA and clinical data of breast cancer, and to evaluate its potential as a breast cancer biomarker.

Methods

The differential expression of circRNAs between the breast cancer tissues and adjacent normal tissues was screened by Human CircRNA Microarray. Candidate circRNAs verified by qRT-PCR. CircRNA was analyzed by Agilent GeneSpring 13.0 software. SPSS23.0, GraphPad Prism, and Sigmaplot software were used for statistical analysis. Perform T test, one-way ANOVA, curve regression analysis and ROC curve analysis for evaluating the diagnostic value of

SUBMITTER: Li X 

PROVIDER: S-EPMC7556178 | biostudies-literature | 2020 Jan-Dec

REPOSITORIES: biostudies-literature