Design and feasibility of a novel program of cervical screening in Nigeria: self-sampled HPV testing paired with visual triage.

ABSTRACT:

Background

Accelerated global control of cervical cancer would require primary prevention with human papillomavirus (HPV) vaccination in addition to novel screening program strategies that are simple, inexpensive, and effective. We present the feasibility and outcome of a community-based HPV self-sampled screening program.

Methods

In Ile Ife, Nigeria, 9406 women aged 30-49 years collected vaginal self-samples, which were tested for HPV in the local study laboratory using Hybrid Capture-2 (HC2) (Qiagen). HPV-positive women were referred to the colposcopy clinic. Gynecologist colposcopic impression dictated immediate management; biopsies were taken when definite acetowhitening was present to produce a histopathologic reference standard of precancer (and to determine final clin

SUBMITTER: Desai KT 

PROVIDER: S-EPMC7556552 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature