Parieto-occipital sulcus widening differentiates posterior cortical atrophy from typical Alzheimer disease.

ABSTRACT:

Objectives

Posterior Cortical Atrophy (PCA) is an atypical presentation of Alzheimer disease (AD) characterized by atrophy of posterior brain regions. This pattern of atrophy is usually evaluated with Koedam visual rating scale, a score developed to enable visual assessment of parietal atrophy on magnetic resonance imaging (MRI). However, Koedam scale is complex to assess and its utility in the differential diagnosis between PCA and typical AD has not been demonstrated yet. The aim of this study is therefore to spot a simple and reliable MRI element able to differentiate between PCA and typical AD using visual rating scales.

Methods

15 patients who presented with progressive complex visual disorders and predominant occipitoparietal hypometabolism on PET-FDG were selected fro

SUBMITTER: Fumagalli GG 

PROVIDER: S-EPMC7559336 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature