Response of extensively drug resistant Salmonella Typhi to treatment with meropenem and azithromycin, in Pakistan.

ABSTRACT:

Introduction

Salmonella Typhi is one of the leading health problems in Pakistan. With the emergence of extensively drug resistant (XDR) Salmonella Typhi, treatment options are limited. Here we report the clinical manifestations and the response to treatment of patients with XDR Typhoid fever. The patients were treated with either Meropenem or Azithromycin or a combination of both.

Methods

We reviewed the records of culture confirmed XDR typhoid who visited Aga Khan University Hospital (AKUH), Karachi and Aga Khan Secondary Care Hospital, Hyderabad from April 2017 to June 2018. Symptoms developed during disease, unplanned treatment extension and complications developed while on antimicrobials was recorded. Means with standard deviation were calculated for duration of treatmen

SUBMITTER: Qureshi S 

PROVIDER: S-EPMC7561124 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature