Study of the differentially abundant proteins among Leishmania amazonensis, L. braziliensis, and L. infantum.

ABSTRACT: Leishmaniasis has been considered as emerging and re-emerging disease, and its increasing global incidence has raised concerns. The great clinical diversity of the disease is mainly determined by the species. In several American countries, tegumentary leishmaniasis (TL) is associated with both Leishmania amazonensis and L. braziliensis, while visceral leishmaniasis (VL) is associated with L. (L.) infantum. The major molecules that determine the most diverse biological variations are proteins. In the present study, through a DIGE approach, we identified differentially abundant proteins among the species mentioned above. We observed a variety of proteins with differential abundance among the studied species; and the biological networks predicted for each species showed that many of these pro

SUBMITTER: Lima BSS 

PROVIDER: S-EPMC7561129 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature