The influence of ACE inhibitors and ARBs on hospital length of stay and survival in people with COVID-19.

ABSTRACT:

Objective

During the COVID-19 pandemic the continuation or cessation of angiotensin-converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARBs) has been contentious. Mechanisms have been proposed for both beneficial and detrimental effects. Recent studies have focused on mortality with no literature having examined length of hospital stay. The aim of this study was to determine the influence of ACEi and ARBs on COVID-19 mortality and length of hospital stay.

Methods

COPE (COVID-19 in Older People) is a multicenter observational study including adults of all ages admitted with either laboratory or clinically confirmed COVID-19. Routinely generated hospital data were collected. Primary outcome: mortality; secondary outcomes: Day-7 mortality and length of hospi

SUBMITTER: Braude P 

PROVIDER: S-EPMC7561344 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature