Mind the Rhythm: ECG QT Dispersion and Cognition in Healthy Older Adults.

ABSTRACT:

Background

Autonomic function has been linked to cognitive abilities in aging. Even in non-clinical states, a certain variability in heart rhythm regulation can be measured with QT dispersion (QTcD), an ECG marker of ventricular repolarization which has been linked to autonomic function and cardiovascular health. QTcD has been shown to be higher in individuals with mild cognitive impairment, and the highest in individuals with Alzheimer's disease. The goal of this study was to see if QTcD is associated with cognitive performance in healthy individuals.

Methods

Sixty-three healthy inactive older adults (> 60 years) completed an extensive cognitive assessment (including inhibition, divided attention, updating, working memory, and processing speed), a physical fitness assessmen

SUBMITTER: Vrinceanu T 

PROVIDER: S-EPMC7561416 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature