Ontology highlight
ABSTRACT:
SUBMITTER: Bagnat M
PROVIDER: S-EPMC7561478 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Bagnat Michel M Gray Ryan S RS
Development (Cambridge, England) 20201006 21
The vertebrate body plan is characterized by the presence of a segmented spine along its main axis. Here, we examine the current understanding of how the axial tissues that are formed during embryonic development give rise to the adult spine and summarize recent advances in the field, largely focused on recent studies in zebrafish, with comparisons to amniotes where appropriate. We discuss recent work illuminating the genetics and biological mechanisms mediating extension and straightening of th ...[more]