Added mass in rat plantaris muscle causes a reduction in mechanical work.

ABSTRACT: Most of what we know about whole muscle behaviour comes from experiments on single fibres or small muscles that are scaled up in size without considering the effects of the additional muscle mass. Previous modelling studies have shown that tissue inertia acts to slow the rate of force development and maximum velocity of muscle during shortening contractions and decreases the work and power per cycle during cyclic contractions; however, these results have not yet been confirmed by experiments on living tissue. Therefore, in this study we conducted in situ work-loop experiments on rat plantaris muscle to determine the effects of increasing the mass of muscle on mechanical work during cyclic contractions. We additionally simulated these experimental contractions using a mass-enhanced H

SUBMITTER: Ross SA 

PROVIDER: S-EPMC7561483 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature