Ontology highlight
ABSTRACT:
SUBMITTER: Faiz A
PROVIDER: S-EPMC7562702 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Scientific reports 20201015 1
Hyperinflation contributes to dyspnea intensity in COPD. Little is known about the molecular mechanisms underlying hyperinflation and how inhaled corticosteroids (ICS) affect this important aspect of COPD pathophysiology. To investigate the effect of ICS/long-acting β<sub>2</sub>-agonist (LABA) treatment on both lung function measures of hyperinflation, and the nasal epithelial gene-expression profile in severe COPD. 117 patients were screened and 60 COPD patients entered a 1-month run-in period ...[more]