The Transcriptomic Landscape of Cupriavidus metallidurans CH34 Acutely Exposed to Copper.

ABSTRACT: Bacteria are increasingly used for biotechnological applications such as bioremediation, biorecovery, bioproduction, and biosensing. The development of strains suited for such applications requires a thorough understanding of their behavior, with a key role for their transcriptomic landscape. We present a thorough analysis of the transcriptome of Cupriavidus metallidurans CH34 cells acutely exposed to copper by tagRNA-sequencing. C. metallidurans CH34 is a model organism for metal resistance, and its potential as a biosensor and candidate for metal bioremediation has been demonstrated in multiple studies. Several metabolic pathways were impacted by Cu exposure, and a broad spectrum of metal resistance mechanisms, not limited to copper-specific clusters, was overexpressed. In

SUBMITTER: Maertens L 

PROVIDER: S-EPMC7563307 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature