Progress in the Development of Subunit Vaccines against Malaria.

ABSTRACT: Malaria is a life-threatening disease and one of the main causes of morbidity and mortality in the human population. The disease also results in a major socio-economic burden. The rapid spread of malaria epidemics in developing countries is exacerbated by the rise in drug-resistant parasites and insecticide-resistant mosquitoes. At present, malaria research is focused mainly on the development of drugs with increased therapeutic effects against Plasmodium parasites. However, a vaccine against the disease is preferable over treatment to achieve long-term control. Trials to develop a safe and effective immunization protocol for the control of malaria have been occurring for decades, and continue on today; still, no effective vaccines are available on the market. Recently, peptide-based vacci

SUBMITTER: Skwarczynski M 

PROVIDER: S-EPMC7563759 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature