Reference Intervals for Platelet Counts in the Elderly: Results from the Prospective SENIORLAB Study.

ABSTRACT: Currently, age- and sex-independent reference limits (RLs) are frequently used to interpret platelet counts in seniors. We aimed to define and validate reference intervals (RIs) for platelet counts within the framework of the prospective SENIORLAB study. Subjectively healthy Swiss individuals aged 60 years and older were prospectively included and followed for morbidity and mortality. Participants who had circumstances known to affect platelet counts were excluded. The obtained RIs were validated with indirect statistical methods. Frequencies of abnormal platelet counts in a population-based setting, including 41.5% of the entire age-specific population of the Principality of Liechtenstein, were compared by using age- and sex-independent RIs and the RLs obtained in the present study. For m

SUBMITTER: Hermann W 

PROVIDER: S-EPMC7564319 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature