The Zebrafish Perivitelline Fluid Provides Maternally-Inherited Defensive Immunity.

ABSTRACT: In the teleost egg, the embryo is immersed in an extraembryonic fluid that fills the space between the embryo and the chorion and partially isolates it from the external environment, called the perivitelline fluid (PVF). The exact composition of the PVF remains unknown in vertebrate animals. The PVF allows the embryo to avoid dehydration, to maintain a safe osmotic balance and provides mechanical protection; however, its potential defensive properties against bacterial pathogens has not been reported. In this work, we determined the global proteomic profile of PVF in zebrafish eggs and embryos, and the maternal or zygotic origin of the identified proteins was studied. In silico analysis of PVF protein composition revealed an enrichment of protein classes associated with non-specific humora

SUBMITTER: De la Paz JF 

PROVIDER: S-EPMC7564447 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature