Risk stratification of hospitalized COVID-19 patients through comparative studies of laboratory results with influenza.

ABSTRACT:

Background

The outbreak of coronavirus disease 2019 (COVID-19) in December 2019 overlaps with the flu season.

Methods

We compared clinical and laboratory results from 719 influenza and 973 COVID-19 patients from January to April 2020. We compiled laboratory results from the first 14 days of the hospitalized patients using parameters that are most significantly different between COVID-19 and influenza and hierarchically clustered COVID-19 patients.

Findings

Compared to influenza, patients with COVID-19 exhibited a continued increase in white blood cell count, rapid decline of hemoglobin, more rapid increase in blood urea nitrogen (BUN) and D-dimer, and higher level of alanine transaminase, C-reactive protein, ferritin, and fibrinogen. COVID-19 patients were sub-classif

SUBMITTER: Mei Y 

PROVIDER: S-EPMC7564523 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature