Remdesivir for Adults With COVID-19 : A Living Systematic Review for American College of Physicians Practice Points.

ABSTRACT:

Background

Few treatments exist for coronavirus disease 2019 (COVID-19).

Purpose

To evaluate the effectiveness and harms of remdesivir for COVID-19.

Data sources

Several databases, tables of contents of journals, and U.S. Food and Drug Administration and company websites were searched from 1 January through 31 August 2020.

Study selection

English-language, randomized trials of remdesivir treatments for adults with suspected or confirmed COVID-19. New evidence will be incorporated using living review methods.

Data extraction

Single-reviewer abstraction and risk-of-bias assessment verified by a second reviewer; GRADE (Grading of Recommendations Assessment, Development and Evaluation) methods used for certainty-of-evidence assessments.

Data synthesis

SUBMITTER: Wilt TJ 

PROVIDER: S-EPMC7564604 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature