Markers Useful in Monitoring Radiation-Induced Lung Injury in Lung Cancer Patients: A Review.

ABSTRACT: In 2018, lung cancer was the most common cancer and the most common cause of cancer death, accounting for a 1.76 million deaths. Radiotherapy (RT) is a widely used and effective non-surgical cancer treatment that induces remission in, and even cures, patients with lung cancer. However, RT faces some restrictions linked to the radioresistance and treatment toxicity, manifesting in radiation-induced lung injury (RILI). About 30-40% of lung cancer patients will develop RILI, which next to the local recurrence and distant metastasis is a substantial challenge to the successful management of lung cancer treatment. These data indicate an urgent need of looking for novel, precise biomarkers of individual response and risk of side effects in the course of RT. The aim of this review was to summariz

SUBMITTER: Sliwinska-Mosson M 

PROVIDER: S-EPMC7565537 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature