Dim Light at Night Induced Neurodegeneration and Ameliorative Effect of Curcumin.

ABSTRACT: It is a well-known fact that following a proper routine light/dark or diurnal rhythm controls almost all biological processes. With the introduction of modern lighting and artificial illumination systems, continuous exposure to light at night may lead to the disruption of diurnal rhythm. However, the effect of light during the night on brain anatomy, physiology, and human body functions is less explored and poorly understood. In this study, we have evaluated the effect of exposure to dim light (5 lux) at night (dLAN) on Swiss Albino mice over a duration of three consecutive weeks. Results have revealed that exposure to dLAN led to an impairment of cognitive and non-cognitive behaviour, oxidative stress-mediated elevation of lipid peroxidation, and reduction of superoxide dismutase and cata

SUBMITTER: Namgyal D 

PROVIDER: S-EPMC7565558 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature