Beyond Chemotherapies: Recent Strategies in Breast Cancer Treatment.

ABSTRACT: In 2018, about 2.1 million women have been diagnosed with breast cancer worldwide. Treatments include-among others-surgery, chemotherapy, radiotherapy, or endocrine therapy. The current policy of care tends rather at therapeutic de-escalation, and systemic treatment such as chemotherapies alone are not systematically considered as the best option anymore. With recent advances in the understanding of cancer biology, and as a complement to anatomic staging, some biological factors (assessed notably via gene-expression signatures) are taken into account to evaluate the benefit of a chemotherapy regimen. The first aim of this review will be to summarize when chemotherapies can be avoided or used only combined with other treatments. The second aim will focus on molecules that can be used instea

SUBMITTER: Foulon A 

PROVIDER: S-EPMC7565588 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature