Immune biomarkers link air pollution exposure to blood pressure in adolescents.

ABSTRACT:

Background

Childhood exposure to air pollution contributes to cardiovascular disease in adulthood. Immune and oxidative stress disturbances might mediate the effects of air pollution on the cardiovascular system, but the underlying mechanisms are poorly understood in adolescents. Therefore, we aimed to identify immune biomarkers linking air pollution exposure and blood pressure levels in adolescents.

Methods

We randomly recruited 100 adolescents (mean age, 16 years) from Fresno, California. Using central-site data, spatial-temporal modeling, and distance weighting exposures to the participant's home, we estimated average pollutant levels [particulate matter (PM), polyaromatic hydrocarbons (PAH), ozone (O₃), carbon monoxide (CO) and nitrogen oxides (NO_x)

SUBMITTER: Prunicki M 

PROVIDER: S-EPMC7566149 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature