Effects of respiratory disease on Kele piglets lung microbiome, assessed through 16S rRNA sequencing.

ABSTRACT:

Background and aim

Due to the incomplete development of the immune system in immature piglets, the respiratory tract is susceptible to invasion by numerous pathogens that cause a range of potential respiratory diseases. However, few studies have reported the changes in pig lung microorganisms during respiratory infection. Therefore, we aimed to explore the differences in lung environmental microorganisms between healthy piglets and piglets with respiratory diseases.

Materials and methods

Histopathological changes in lung sections were observed in both diseased and healthy pigs. Changes in the composition and abundance of microbiomes in alveolar lavage fluid from eleven 4-week-old Chinese Kele piglets (three clinically healthy and eight diseased) were studied by IonS5™ XL seq

SUBMITTER: Zhang J 

PROVIDER: S-EPMC7566272 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature