A Simple Flow Classification Parameter Can Discriminate Rupture Status in Intracranial Aneurysms.

ABSTRACT:

Background

A simple dimensionless aneurysm number ($An$), which depends on geometry and flow pulsatility, was previously shown to distinguish the flow mode in intracranial aneurysms (IA): vortex mode with a dynamic vortex formation/evolution if $An > 1$, and cavity mode with a steady shear layer if $An < 1$.

Objective

To hypothesize that $An\ > \ 1$ can distinguish rupture status because vortex mode is associated with high oscillatory shear index, which, in turn, is statistically associated with rupture.

Methods

The above hypothesis is tested on a retrospective, consecutively collected database of 204 patient-specific IAs. The first 119 cases are assigned to training and the remainder to testing dataset. $An$ is calculated based on the pulsatility index (PI) approxima

SUBMITTER: Asgharzadeh H 

PROVIDER: S-EPMC7566542 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature