Prevalence and impact of comorbidities in axial spondyloarthritis: systematic review and meta-analysis.

ABSTRACT:

Objectives

Comorbidities are common in people with axial spondyloarthritis (axSpA). In this systematic review and meta-analysis, we aimed to: (i) describe the prevalence of commonly reported comorbidities, (ii) compare comorbidities between axSpA and control populations, and (iii) examine the impact of comorbidity burden on axSpA outcomes.

Methods

We systematically searched Medline, PubMed, Scopus and Web of Science using a predefined protocol in accordance with Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. We excluded studies of only one comorbid condition or a few closely related diseases within one organ system. Where possible, meta-analysis was performed using random-effects models.

Results

A total of 40 studies were inclu

SUBMITTER: Zhao SS 

PROVIDER: S-EPMC7566561 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature