Publication bias in pediatric emergence delirium: a cross-sectional analysis of ClinicalTrials.gov and ClinicalTrialsRegister.eu.

ABSTRACT:

Objectives

Emergence delirium (ED) is a frequent and potentially serious complication of general anaesthesia in children. Although there are various treatment strategies, no general management recommendations can be made. Selective reporting of study results may impair clinical decision-making. We, therefore, analysed whether the results of completed registered clinical studies in patients with paediatric ED are publicly available or remain unpublished.

Design

Cross-sectional analysis.

Setting

ClinicalTrials.gov and ClinicalTrialsRegister.eu.

Participants and outcome measures

We determined the proportion of published and unpublished studies registered at ClinicalTrials.gov and ClinicalTrialsRegister.eu that were marked as completed by 1st September 2018. The ma

SUBMITTER: Meyburg J 

PROVIDER: S-EPMC7566730 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature