Liver disease and outcomes among COVID-19 hospitalized patients - A systematic review and meta-analysis.

ABSTRACT:

Introduction and objectives

The coronavirus disease 2019 (COVID-19) pandemic has been a challenge globally. In severe acute respiratory syndrome (SARS) epidemic 60% of patients had hepatic injury, due to phylogenetic similarities of the viruses it is assumed that COVID-19 is associated with acute liver injury. In this meta-analysis, we aim to study the occurrence and association of liver injury, comorbid liver disease and elevated liver enzymes in COVID-19 confirmed hospitalizations with outcomes.

Materials and methods

Data from observational studies describing comorbid chronic liver disease, acute liver injury, elevated aspartate aminotransferase (AST), alanine aminotransferase (ALT) levels and outcomes of COVID-19 hospitalized patients from December 1, 2019, to June 30, 20

SUBMITTER: Sharma A 

PROVIDER: S-EPMC7566821 | biostudies-literature | 2021 Mar-Apr

REPOSITORIES: biostudies-literature