Ontology highlight
ABSTRACT:
SUBMITTER: Fan X
PROVIDER: S-EPMC7566847 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Neoplasia (New York, N.Y.) 20201013 11
Aberrant methylation is a hallmark of hepatocellular carcinoma and plays an important role in tumor initiation and progression. However, the epigenome-wide methylation patterns of portal vein tumor thrombosis (PVTTs) have not been fully explored. Here, we performed epigenome-wide DNA methylation of adjacent normal tissues (ANTs), paired tumor tissues and paired PVTTs using an Infinium HumanMethylation450 array (n = 11) and conducted the Sequenom EpiTYPER assays to confirm the aberrantly methylat ...[more]