Prognostic impact of myosteatosis in patients with colorectal cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

Myosteatosis has been reported to be a novel biomarker that could predict survival outcomes in patients with colorectal cancer. However, results have been conflicting. This systematic review and meta-analysis aimed to evaluate the long-term impact of myosteatosis on the survival of these patients.

Methods

A systematic search of PubMed, Embase, and Cochrane up to 27 November 2019 generated 7022 records. Studies that reported hazard ratio (HR) for overall survival, cancer-specific survival, or disease-free survival based on myosteatosis or radiodensity were included. A total of 110 full-text articles were considered for inclusion, and 14 were selected for qualitative analysis. Inverse variance method was used with random effects model for data analysis.

Results</

SUBMITTER: Lee CM 

PROVIDER: S-EPMC7567135 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature