Specific features and assembly of the plant mitochondrial complex I revealed by cryo-EM.

ABSTRACT: Mitochondria are the powerhouses of eukaryotic cells and the site of essential metabolic reactions. Complex I or NADH:ubiquinone oxidoreductase is the main entry site for electrons into the mitochondrial respiratory chain and constitutes the largest of the respiratory complexes. Its structure and composition vary across eukaryote species. However, high resolution structures are available only for one group of eukaryotes, opisthokonts. In plants, only biochemical studies were carried out, already hinting at the peculiar composition of complex I in the green lineage. Here, we report several cryo-electron microscopy structures of the plant mitochondrial complex I. We describe the structure and composition of the plant respiratory complex I, including the ancestral mitochondrial domain compose

SUBMITTER: Soufari H 

PROVIDER: S-EPMC7567890 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature